Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MLLT1 | Q03111 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659986 | 0.87 | NPC1 (0.35) | NPC1RAB9AALDH1A1TP53MAPK1 | |
| SCHEMBL298058 | 0.78 | CHRM2 (0.44) | HSD17B1HSD17B2NPC1RAB9AALDH1A1 | |
| SCHEMBL287429 | 0.75 | NPSR1 (0.36) | NPC1RAB9AALDH1A1TP53MAPK1 | |
| SCHEMBL297726 | 0.73 | MAPT (0.38) | NPC1RAB9AALDH1A1TP53MAPK1 | |
| SCHEMBL298661 | 0.72 | KMT2A (0.37) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7808911 | 0.69 | ALDH1A1 (0.48) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL661687 | 0.68 | ERCC5 (0.43) | NPC1RAB9AALDH1A1TP53MAPK1 | |
| SCHEMBL660685 | 0.68 | ALDH1A1 (0.40) | NPC1RAB9AALDH1A1TP53MAPK1 | |
| SCHEMBL660093 | 0.68 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5728908 | 0.68 | HSD17B1 (0.84) | HSD17B1HSD17B2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | claimed |
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | HSD17B1 2273/4885HSD17B2 2995/4885NPC1 1176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.