Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611523 | 0.75 | PKM (0.33) | L3MBTL1SMN1; SMN2LMNAHTTTSHR | |
| SCHEMBL9320429 | 0.70 | ALDH1A1 (0.51) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL8750311 | 0.70 | MEN1 (0.35) | GAAL3MBTL1TDP1KMT2ALMNA | |
| SCHEMBL13883863 | 0.66 | HPGD (0.65) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL2187456 | 0.66 | ALDH1A1 (0.59) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL2185746 | 0.64 | KDM4E (1.00) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL2185749 | 0.64 | ALDH1A1 (0.60) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL7827343 | 0.63 | ALDH1A1 (0.59) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL7827972 | 0.62 | ALDH1A1 (0.55) | ALDH1A1GAAKDM4EHPGDGLA | |
| SCHEMBL2186719 | 0.61 | KDM4E (0.76) | ALDH1A1GAAKDM4EHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395566-A1 | TRICYCLIC COMPOUNDS USEFUL AS ANGIOTENSIN II AGONISTS | Vicore Pharma AB (SE) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002096883-A1 | TRICYCLIC COMPOUNDS USEFUL AS ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2002-12-05 | — | — | WO | disclosed |