Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.30 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | MMP14 | P50281 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7265688 | 0.79 | LMNA (0.37) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL6612249 | 0.75 | ALDH1A1 (0.46) | LMNATSHRHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7260194 | 0.71 | EDNRB (0.38) | LMNASMN1; SMN2CA12CA9 | |
| SCHEMBL8750311 | 0.69 | MEN1 (0.35) | LMNAL3MBTL1 | |
| SCHEMBL8645010 | 0.65 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL10463947 | 0.65 | ALDH1A1 (0.40) | LMNASMN1; SMN2 | |
| SCHEMBL710923 | 0.65 | AGTR2 (0.32) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL10616070 | 0.64 | NSD2 (0.46) | LMNASMN1; SMN2 | |
| SCHEMBL10465325 | 0.64 | SMN1; SMN2 (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL8642432 | 0.63 | ALDH1A1 (0.36) | LMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046141-A1 | NEW TRICYCLIC ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2004-06-03 | — | — | WO | disclosed |
| WO-2004046137-A1 | NEW TRICYCLIC ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2004-06-03 | — | — | WO | disclosed |
| EP-1395566-A1 | TRICYCLIC COMPOUNDS USEFUL AS ANGIOTENSIN II AGONISTS | Vicore Pharma AB (SE) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002096883-A1 | TRICYCLIC COMPOUNDS USEFUL AS ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2002-12-05 | — | — | WO | disclosed |