Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269013 | 0.93 | LMNA (0.72) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL6130576 | 0.88 | LMNA (0.48) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL5288853 | 0.87 | LMNA (0.60) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL268888 | 0.87 | NPC1 (0.70) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL10932866 | 0.85 | NPC1 (0.64) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL7832117 | 0.85 | NPC1 (0.58) | LMNAHSD17B10ALDH1A1NPC1RAB9A | |
| SCHEMBL3795638 | 0.84 | ALDH1A1 (0.60) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL6256138 | 0.81 | ALDH1A1 (0.43) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL19879283 | 0.80 | LMNA (0.70) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL5771884 | 0.80 | NR1H4 (0.45) | LMNAHSD17B10ALOX15ALDH1A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100447-B1 | SUNSCREEN COMPOSITIONS | PROCTER & GAMBLE (US) | 2004-05-12 | — | — | EP | claimed |