Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270608 | 0.90 | LMNA (0.73) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL268888 | 0.88 | NPC1 (0.70) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL6614760 | 0.87 | LMNA (0.62) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL6130576 | 0.87 | LMNA (0.48) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL5159215 | 0.81 | LMNA (0.71) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL6256138 | 0.80 | ALDH1A1 (0.43) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL269013 | 0.79 | LMNA (0.72) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL7832117 | 0.79 | NPC1 (0.58) | LMNAHSD17B10ALDH1A1NPC1RAB9A | |
| SCHEMBL10932866 | 0.79 | NPC1 (0.64) | LMNAHSD17B10ALOX15ALDH1A1APEX1 | |
| SCHEMBL8984984 | 0.78 | ALOX15 (0.69) | LMNAHSD17B10ALOX15ALDH1A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008575-A1 | COSMETIC COMPOSITIONS CONTAINING LIPOSOLUBLE POLYMERS AND TACKIFIERS | L'OREAL (FR) | 2007-01-18 | — | — | WO | disclosed |