Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4663944 | 0.85 | MAPT (0.43) | NR1H4MAPTLMNATDP1ALDH1A1 | |
| SCHEMBL2268368 | 0.82 | MAPT (0.47) | NR1H4MAPTLMNATDP1ALDH1A1 | |
| SCHEMBL17836545 | 0.80 | MAPT (0.43) | MAPTLMNAALDH1A1MAPK1NPC1 | |
| SCHEMBL6614760 | 0.80 | LMNA (0.62) | NR1H4MAPTLMNATDP1ALDH1A1 | |
| SCHEMBL7162385 | 0.73 | MAPT (0.60) | NR1H4MAPTLMNATDP1ALDH1A1 | |
| SCHEMBL269013 | 0.73 | LMNA (0.72) | NR1H4MAPTLMNATDP1ALDH1A1 | |
| SCHEMBL6130576 | 0.72 | LMNA (0.48) | NR1H4MAPTLMNATDP1ALDH1A1 | |
| SCHEMBL11576344 | 0.71 | MAPT (0.56) | NR1H4MAPTLMNATDP1ALDH1A1 | |
| SCHEMBL9857167 | 0.70 | NPC1 (0.63) | MAPTLMNAALDH1A1MAPK1NPC1 | |
| SCHEMBL5288853 | 0.69 | LMNA (0.60) | NR1H4MAPTLMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587150-A | Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate | L'OREAL (FR) | 1996-12-24 | — | — | US | claimed |
| EP-2531263-B1 | A PHOTOSTABLE SUNSCREEN COMPOSITION | UNILEVER NV (NL) | 2016-06-22 | — | — | EP | disclosed |
| EP-1635777-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004105712-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |