Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28427527 | 0.98 | HDAC8 (0.67) | HDAC8HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| Acetic Acid SCHEMBL8172858 | 0.94 | SMN1; SMN2 (0.64) | HDAC8HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| Benzoic Acid Hydrazide SCHEMBL11833590 | 0.94 | SMN1; SMN2 (0.74) | HDAC8HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28283623 | 0.93 | HDAC8 (0.61) | HDAC8HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| Water SCHEMBL8856536 | 0.86 | SMN1; SMN2 (0.54) | HDAC8HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL77384 | 0.85 | ALDH1A1 (0.76) | HDAC8HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL24931248 | 0.83 | SMN1; SMN2 (0.89) | HDAC8HDAC6SMN1; SMN2ALDH1A1MEN1 | |
| Benzoic Acid Hydrazide SCHEMBL8180423 | 0.82 | SMN1; SMN2 (0.58) | HDAC8HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| Benzoic Acid Hydrazide SCHEMBL7199126 | 0.82 | LMNA (0.61) | HDAC8HDAC6SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30929655 | 0.82 | HDAC6 (1.00) | HDAC8HDAC6SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121426-B | Synthesis method of myrtenal aldehyde group dihydrazide compounds with fungal inhibition activity | 广西大学 | 2023-01-06 | — | — | CN | claimed |
| CN-110003160-B | Osthole hydrazone/acylhydrazone/sulfonylhydrazone derivatives, and preparation method and application thereof | 贵州中医药大学 | 2022-10-11 | — | — | CN | claimed |
| CN-114875394-A | Corrosion and scale inhibition zinc series metal phosphate conversion agent and preparation method thereof | 安徽未来表面技术有限公司 | 2022-08-09 | — | — | CN | claimed |
| CN-113121382-A | Metal compound material and preparation method thereof, quantum dot light-emitting diode and light-emitting device | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| CN-113121426-A | Synthesis method of myrtenal aldehyde group dihydrazide compounds with fungal inhibition activity | 广西大学 | 2021-07-16 | — | — | CN | claimed |
| CN-108997142-B | Method for removing residual ketone in production of fatty amine by ketone method | 浙江建业化工股份有限公司 | 2021-01-12 | — | — | CN | claimed |
| US-7781542-B2 | Curing a mixture of a polyepoxide or epoxy resin, an imidazole curing agent, and an aromatic monofunctional acid hydrazide cure accelerator; reduced gel time | HEXCEL COMPOSITES, LTD. (GB) | 2010-08-24 | — | — | US | claimed |
| EP-1602678-B9 | Cure accelerators | HEXCEL COMPOSITES LTD (GB) | 2008-11-05 | — | — | EP | claimed |
| EP-1602678-B1 | Cure accelerators | HEXCEL COMPOSITES LTD (GB) | 2008-06-11 | — | — | EP | claimed |
| EP-1392219-A4 | SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOTOSIS AND THE USE THEREOF | CYTOVIA INC (US) | 2007-01-24 | — | — | EP | claimed |
| WO-2002089745-A2 | SUBSTITUTED N'-(ARYLCARBONYL)-BENZHYDRAZIDES, N'-(ARYLCARBONYL)-BENZYLIDENE-HYDRAZIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF | CYTOVIA, INC. (US) | 2002-11-14 | — | — | WO | claimed |
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. | 2002-09-12 | — | — | US | claimed |
| WO-2002038667-A2 | NATURAL RUBBER PRODUCED FROM LATEX AND COMPOSITION COMPRISING THE SAME | BRIDGESTONE CORPORATION (JP) | 2002-05-16 | — | — | WO | claimed |
| US-20020035195-A1 | Viscosity-stabilizer-containing natural rubber latex and natural rubber and a production process thereof | BRIDGESTONE CORPORATION | 2002-03-21 | — | — | US | claimed |
| CN-1030911-C | Dibenzoylalkylcyanohydrazines | ROHM & HAAS (US) | 1996-02-07 | — | — | CN | claimed |
| CN-1057452-A | Dibenzoyl alkyl-alkyl cyanides | ROHM & HAAS (US) | 1992-01-01 | — | — | CN | claimed |
| EP-0347216-A2 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acylhydrazines and N'-substituted -N-acyl-N'-alkylcarbonyl hydrazines | ROHM AND HAAS COMPANY (US) | 1989-12-20 | — | — | EP | claimed |
| EP-0123066-B1 | REACTION OF CARBONYLHYDRAZINES AND ORGANIC PEROXIDES TO FOAM UNSATURATED POLYESTER RESINS | PENNWALT CORPORATION (US) | 1988-10-12 | — | — | EP | claimed |
| EP-0220364-A2 | Reaction of certain hydrazide compounds with free radical initiators to produce crosslinked polymer foams | PENNWALT CORPORATION (US) | 1987-05-06 | — | — | EP | claimed |
| US-4607060-A | FREE RADICAL CATALYSIS | PENNWALT CORPORATION (US) | 1986-08-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128292-A1 | Substituted indole-2-carboxylic acid benzylidene-hydrazides and analogs as activators of caspases and inducers of apoptosis and the use thereof | BAD, API5, CASP2 | HDAC8 290/4885HDAC6 171/4885SMN1; SMN2 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.