Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616860 | 1.00 | L3MBTL1 (0.39) | L3MBTL1POLBCTDSP1NPC1CYP1A2 | |
| SCHEMBL8117078 | 0.90 | MKNK1 (0.38) | L3MBTL1POLBCTDSP1NPC1CYP1A2 | |
| SCHEMBL6618464 | 0.80 | ROCK2 (0.49) | FGFR1DYRK3CLK1CLK2CLK3 | |
| SCHEMBL6618856 | 0.80 | ROCK2 (0.49) | FGFR1DYRK3CLK1CLK2CLK3 | |
| SCHEMBL6617033 | 0.79 | ROCK2 (0.49) | FGFR1DYRK3CLK1CLK2CLK3 | |
| SCHEMBL6615880 | 0.79 | CYSLTR1 (0.46) | NPC1RAB9ASMN1; SMN2FGFR1DYRK3 | |
| SCHEMBL6616216 | 0.79 | CYSLTR1 (0.46) | NPC1RAB9ASMN1; SMN2FGFR1DYRK3 | |
| SCHEMBL6617440 | 0.79 | ROCK2 (0.49) | FGFR1DYRK3CLK1CLK2CLK3 | |
| SCHEMBL6621982 | 0.77 | HTT (0.56) | NPC1RAB9ASMN1; SMN2FGFR1DYRK3 | |
| SCHEMBL6617837 | 0.77 | HTT (0.56) | NPC1RAB9ASMN1; SMN2FGFR1DYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0779889-B1 | PYRAZOLO 3,4-g]QUINOXALINE COMPOUNDS WHICH INHIBIT PDGF RECEPTOR PROTEIN TYROSINE KINASE | AVENTIS PHARMA INC (US) | 2004-06-23 | — | — | EP | disclosed |
| US-5476851-A | Administering as therapeutic agents for various disease states which are characterized by uncontrolled cellular proliferation | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1995-12-19 | — | — | US | disclosed |