Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221941 | 0.85 | CA1 (0.43) | CYP3A4TRPA1GABRA1GABRB2TDP1 | |
| SCHEMBL16779903 | 0.83 | GABRA1 (0.35) | CYP3A4TRPA1GABRA1GABRB2GABRB1 | |
| SCHEMBL3675026 | 0.83 | FABP4 (0.44) | GABRA1GABRB2ALDH1A1GABRB1 | |
| SCHEMBL7145360 | 0.83 | GABRA1 (0.48) | GABRA1GABRB2GABRB1 | |
| SCHEMBL20635011 | 0.82 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL6866102 | 0.82 | GABRA1 (0.47) | GABRA1GABRB2MAPK1TDP1GABRB1 | |
| SCHEMBL403988 | 0.80 | CYP3A4 (0.39) | CYP3A4GABRA1GABRB2TSHR | |
| SCHEMBL24891310 | 0.79 | CYP3A4 (0.38) | CYP3A4TRPA1GABRA1GABRB2MAPK1 | |
| SCHEMBL194319 | 0.79 | GABRA1 (0.35) | GABRA1GABRB2GABRB1 | |
| SCHEMBL16779895 | 0.79 | GABRA1 (0.44) | CYP3A4GABRA1GABRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3470452-B1 | METHOD FOR MANUFACTURING CAST POLYAMIDES | LANXESS DEUTSCHLAND GMBH (DE) | 2021-05-19 | — | — | EP | claimed |
| US-9738755-B2 | Molding polyamides, methods for the production thereof, and use thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2017-08-22 | — | — | US | disclosed |
| US-9452975-B2 | Biobased carbodiimides, a process for preparation thereof and use thereof | RHEIN CHEMIE RHEINAU GMBH (DE) | 2016-09-27 | — | — | US | disclosed |
| US-9428611-B2 | Catalysts for producing cast polyamide, method for the production of said catalysts and the use thereof | RHEIN CHEMIE RHEINAU GMBH (DE) | 2016-08-30 | — | — | US | disclosed |
| US-9321879-B2 | Methods for controlling (extending) the pot life in chain-extended polyurethane (PU)-based systems | Rhein Chemie Rheinau, GmbH (DE) | 2016-04-26 | — | — | US | disclosed |
| US-20150322204-A1 | CATALYSTS FOR PRODUCING CAST POLYAMIDE, METHOD FOR THE PRODUCTION OF SAID CATALYSTS AND THE USE THEREOF | LANXESS DEUTSCHLAND GMBH (DE) | 2015-11-12 | — | — | US | disclosed |
| US-20150218314-A1 | MOLDING POLYAMIDES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF | RHEIN CHEMIE RHEINAU GMBH (DE) | 2015-08-06 | — | — | US | disclosed |
| US-20150126688-A1 | METHODS FOR CONTROLLING (EXTENDING) THE POT LIFE IN CHAIN-EXTENDED POLYURETHANE (PU)-BASED SYSTEMS | LANXESS DEUTSCHLAND GMBH (DE) | 2015-05-07 | — | — | US | disclosed |
| US-20140323754-A1 | BIOBASED CARBODIIMIDES, A PROCESS FOR PREPARATION THEREOF AND USE THEREOF | RHEIN CHEMIE RHEINAU GMBH (DE) | 2014-10-30 | — | — | US | disclosed |
| US-20140225032-A1 | METHOD OF PRODUCTION OF CAST POLYAMIDES | RHEIN CHEMIE RHEINAU GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| EP-2256165-A1 | RESIN COMPOSITION AND MOLDED ARTICLE | Teijin Limited (JP) | 2010-12-01 | — | — | EP | disclosed |
| US-20100182694-A1 | FILM | TEIJIN LIMITED (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-2189493-A1 | FILM | Teijin Limited (JP) | 2010-05-26 | — | — | EP | disclosed |
| US-20100093888-A1 | POLYLACTIC ACID COMPOSITION | TEIJIN LIMITED (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20090306332-A1 | PREPARATION OF CAST POLYAMIDES USING SPECIAL ACTIVATORS | RHEIN CHEMIE RHEINAU GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-2116576-A1 | POLYLACTIC ACID COMPOSITION | Teijin Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| CN-101538364-A | Preparation of cast polyamides using special activators | RHEIN CHEMIE RHEINAU GMBH | 2009-09-23 | — | — | CN | disclosed |
| EP-2053091-A1 | RESIN COMPOSITION, METHOD FOR PRODUCING THE SAME AND MOLDED ARTICLE | TEIJIN LIMITED (JP) | 2009-04-29 | — | — | EP | disclosed |
| EP-0658639-B1 | Multifilament yarn having high resistance to hydrolysis and aminolysis made from a polyester on the basis of poly(1,4-bis-methylene cyclohexane terephthalate) and process for its production | ARTEVA TECH SARL (CH) | 2001-03-21 | — | — | EP | disclosed |
| US-5518813-A | HYDROLYSIS AND AMMONOLYSIS RESISTANT | HOECHST AKTINEGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323754-A1 | BIOBASED CARBODIIMIDES, A PROCESS FOR PREPARATION THEREOF AND USE THEREOF | OTUB1, CBR3, BBOX1 | CYP3A4 69/4885TRPA1 4145/4885GABRA1 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.