Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669302 | 0.75 | HTT (0.36) | MAPK1TAS1R3TAS1R1ABCB1KCNH2 | |
| SCHEMBL9448494 | 0.73 | KDM4E (0.55) | — | |
| SCHEMBL4685166 | 0.73 | KDM4E (0.55) | — | |
| SCHEMBL4685164 | 0.73 | KDM4E (0.55) | — | |
| SCHEMBL25211177 | 0.72 | MAPK1 (0.51) | MAPK1TAS1R3TAS1R1KCNH2SLC6A2 | |
| SCHEMBL9484082 | 0.71 | ADRB1 (0.60) | CYP3A4LMNA | |
| SCHEMBL25199161 | 0.69 | TOP2A (0.51) | MAPK1TAS1R3TAS1R1KCNH2GAA | |
| SCHEMBL4684232 | 0.69 | MAPK1 (0.49) | MAPK1TAS1R3TAS1R1KCNH2SLC6A2 | |
| SCHEMBL661839 | 0.69 | LMNA (0.52) | CYP3A4LMNAPOLBSMN1; SMN2 | |
| SCHEMBL16605596 | 0.69 | PARP10 (0.56) | MAPK1KCNH2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120045505-A1 | FIXED DOSE DRUG COMBINATION FORMULATIONS | DR. REDDY'S LABORATORIES, INC. (US) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120045505-A1 | FIXED DOSE DRUG COMBINATION FORMULATIONS | SLC5A6, TNNT2, SIRT6 | MAPK1 4412/4885TAS1R3 1653/4885TAS1R1 1820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.