Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6647024 | 0.90 | SSTR5 (0.47) | MEN1KMT2AKDM4ELMNAPOLB | |
| SCHEMBL6617305 | 0.85 | CHRNB4 (0.47) | POLBALDH1A1 | |
| SCHEMBL4049636 | 0.85 | MEN1 (0.46) | MEN1KMT2AKDM4ELMNAPOLB | |
| SCHEMBL6619348 | 0.81 | CHRNB4 (0.47) | POLBMAPTCCR3ALDH1A1 | |
| SCHEMBL6617259 | 0.81 | CHRNB4 (0.42) | POLBCCR3ALDH1A1 | |
| SCHEMBL6614953 | 0.77 | KDM4E (0.40) | KDM4EPOLBCCR3ALDH1A1MAOA | |
| SCHEMBL6618307 | 0.77 | CACNA1B (0.44) | CCR3MAOB | |
| SCHEMBL6648474 | 0.76 | PTGS1 (0.46) | CCR3KCNH2 | |
| SCHEMBL6659265 | 0.76 | POLB (0.44) | KDM4ELMNAPOLB | |
| SCHEMBL6614327 | 0.75 | CYP3A4 (0.48) | MEN1KMT2ACCR3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421070-A1 | NEW PIPERIDINYL DERIVATES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | AstraZeneca AB (SE) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003018566-A1 | NEW PIPERIDINYL DERIVATES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | ASTRAZENECA AB (SE) | 2003-03-06 | — | — | WO | disclosed |