Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | ABL2 | P42684 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618798 | 0.92 | ADH1A (0.46) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL24065613 | 0.87 | ADH1A (0.40) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL7945647 | 0.83 | ADH1A (0.45) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL30360049 | 0.81 | P4HB (0.51) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL7952123 | 0.81 | HRH4 (0.44) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL30852737 | 0.81 | P4HB (0.51) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL7959056 | 0.81 | KMT2A (0.45) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL19057483 | 0.81 | P4HB (0.51) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL18822196 | 0.81 | P4HB (0.51) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL7954292 | 0.81 | ADH1A (0.32) | ADH1AKITFLT1KDRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983248-B1 | ANALOGS OF DUOCARMYCIN AND CC-1065 | SCRIPPS RESEARCH INST (US) | 2004-07-14 | — | — | EP | disclosed |
| US-6281354-B1 | ANTIBIOTICS; ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-28 | — | — | US | disclosed |