Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | ABL2 | P42684 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952298 | 0.82 | UCHL1 (0.34) | HDAC1HDAC6 | |
| SCHEMBL6618596 | 0.81 | ADH1A (0.46) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL6852340 | 0.81 | ADH1A (0.44) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL7945633 | 0.79 | UCHL1 (0.34) | HDAC1HDAC6 | |
| SCHEMBL6206095 | 0.78 | XDH (0.40) | HDAC1HDAC6NR1H2 | |
| SCHEMBL6618798 | 0.77 | ADH1A (0.46) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL7546805 | 0.76 | ADH1A (0.38) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL6205393 | 0.75 | HDAC1 (0.35) | HDAC1HDAC6NR1H2 | |
| SCHEMBL8131361 | 0.74 | AR (0.37) | ADH1AKITFLT1KDRABL2 | |
| SCHEMBL24065613 | 0.73 | ADH1A (0.40) | ADH1AKITFLT1KDRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281354-B1 | ANTIBIOTICS; ANTITUMOR AGENTS | THE SCRIPPS RESEARCH INSTITUTE | 2001-08-28 | — | — | US | disclosed |