Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.68 |
| ▸ | CA2 | P00918 | 4/20 | 0.68 |
| ▸ | CA7 | P43166 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dimethoxybenzene SCHEMBL10453010 | 0.90 | CA1 (0.62) | CA1CA2CA7CA9CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL27865611 | 0.89 | CA12 (0.54) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3904409 | 0.86 | NFE2L2 (0.51) | CA1CA2CA7CA9CA12 | |
| Guaiacol SCHEMBL27732358 | 0.84 | CA1 (0.75) | CA1CA2CA7CA9CA12 | |
| SCHEMBL1611608 | 0.84 | CA1 (0.48) | CA1CA2CA7CA9CA12 | |
| SCHEMBL2494769 | 0.83 | SMN1; SMN2 (0.48) | CA1CA2CA7CA9CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL105872 | 0.83 | CA1 (1.00) | CA1CA2CA7CA9CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL5308636 | 0.83 | CA1 (1.00) | CA1CA2CA7CA9CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL29351917 | 0.83 | CA1 (1.00) | CA1CA2CA7CA9CA12 | |
| SCHEMBL74380 | 0.81 | HTR6 (0.60) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516987-B | Preparation method of avibactam intermediate | 江西富祥药业股份有限公司 | 2020-07-24 | — | — | CN | claimed |
| US-20240413334-A1 | BINDER AND LITHIUM-ION BATTERY INCLUDING SAME | ZHUHAI COSMX BATTERY CO., LTD. (CN) | 2024-12-12 | — | — | US | disclosed |
| CN-114591312-B | Sulfone and sulfoxide compounds, preparation method and medical application thereof | 中国药科大学 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022018462-A1 | CATECHOL BASED DERIVATIVES FOR USE IN THE PREVENTION OF DNA DAMAGE | UNIVERSITY OF NEWCASTLE UPON TYNE (GB) | 2022-01-27 | — | — | WO | disclosed |
| EP-3212613-B1 | (Z)-3,4,5-TRIMETHOXYSTYRYLBENZENESULFONAMIDES AS POTENTIAL ANTICANCER AGENTS | COUNCIL SCIENT IND RES (IN) | 2020-12-16 | — | — | EP | disclosed |
| CN-109761980-B | 3-aminosulfonylamino-substituted rutaecarpine derivative and preparation method and application thereof | 安徽医科大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-110256305-A | A kind of naphthalenesulfonamide compound, preparation method and application | 中国药科大学 | 2019-09-20 | — | — | CN | disclosed |
| US-10246411-B2 | (Z)-3,4,5-trimethoxystyrylbenzenesulfonamides as potential anticancer agents | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-04-02 | — | — | US | disclosed |
| US-20170327462-A1 | (Z)-3,4,5-TRIMETHOXYSTYRYLBENZENESULFONAMIDES AS POTENTIAL ANTICANCER AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-11-16 | — | — | US | disclosed |
| EP-3212613-A1 | (Z)-3,4,5-TRIMETHOXYSTYRYLBENZENESULFONAMIDES AS POTENTIAL ANTICANCER AGENTS | Council of Scientific and Industrial Research (IN) | 2017-09-06 | — | — | EP | disclosed |
| WO-1999026616-A1 | BENZENESULFONAMIDE INHIBITORS OF PDE-IV AND THEIR THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |
| CN-1207095-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 1999-02-03 | — | — | CN | disclosed |
| CN-1176101-A | N -(4 -aryl -thiazol -2 -yl) -sulphonamide derivatives and their use | HOFFMANN LA ROCHE (CH) | 1998-03-18 | — | — | CN | disclosed |
| US-5728712-A | 3,4-disubstituted-phenylsulphonamides and their therapeutic use | CHIROSCIENCE LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| WO-1998008815-A1 | SUBSTITUTED CYCLIC AMINE METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| WO-1996036611-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |
| EP-0412763-B1 | Cephalosporins, processes for their preparation, pharmaceutical compositions containing them and intermediates therefor | ZENECA LTD (GB) | 1996-07-10 | — | — | EP | disclosed |
| US-5219848-A | Bactericides | ICI PHARMA (FR) | 1993-06-15 | — | — | US | disclosed |
| EP-0412763-A2 | Cephalosporins, processes for their preparation, pharmaceutical compositions containing them and intermediates therefor | ZENECA LIMITED (GB) | 1991-02-13 | — | — | EP | disclosed |
| US-4720580-A | N-(aminoalkylene)benzenesulfonamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246411-B2 | (Z)-3,4,5-trimethoxystyrylbenzenesulfonamides as potential anticancer agents | BCL3, CASP3, HCCS | CA1 1312/4885CA2 1347/4885CA7 163/4885 |
| US-20170327462-A1 | (Z)-3,4,5-TRIMETHOXYSTYRYLBENZENESULFONAMIDES AS POTENTIAL ANTICANCER AGENTS | BCL3, CASP3, HCCS | CA1 2478/4885CA2 2281/4885CA7 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.