Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682355 | 0.80 | CYP1A2 (0.54) | CYP1A2TSHRCYP2A6ACP3ALDH1A1 | |
| SCHEMBL6621589 | 0.79 | CYP1A2 (0.46) | CYP1A2TSHRCYP2A6ACP3ALDH1A1 | |
| SCHEMBL5950131 | 0.79 | MAPT (0.50) | CYP1A2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL18242403 | 0.78 | CYP1A2 (0.52) | CYP1A2TSHRCYP2A6ACP3ALDH1A1 | |
| SCHEMBL5950064 | 0.75 | L3MBTL1 (0.45) | CYP1A2TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL840498 | 0.75 | CA1 (0.39) | CYP1A2TSHRCYP2A6ALDH1A1TDP1 | |
| SCHEMBL11045725 | 0.74 | LMNA (0.38) | CYP1A2TSHRCYP2A6ACP3ALDH1A1 | |
| SCHEMBL2126761 | 0.74 | CYP1A2 (0.56) | CYP1A2TSHRCYP2A6ACP3ALDH1A1 | |
| SCHEMBL5236808 | 0.71 | CYP1A2 (0.48) | CYP1A2TSHRCYP2A6ALDH1A1CYP2C9 | |
| SCHEMBL1707630 | 0.71 | CYP2A6 (0.52) | CYP1A2TSHRCYP2A6ACP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474140-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | Pharmagene Laboratories Ltd (GB) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068226-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |