Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319118 | 0.78 | CYP1A2 (0.59) | CYP1A2CYP2A6KDM4EMAPTPABPC1 | |
| SCHEMBL5241189 | 0.78 | ALDH1A1 (0.32) | CYP1A2ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL5949775 | 0.77 | IMPDH2 (0.45) | CYP1A2KDM4EMAPTALDH1A1CYP2C9 | |
| SCHEMBL168886 | 0.76 | ESR1 (0.45) | MAPTALDH1A1TSHRGRIN2DGRIN3B | |
| SCHEMBL7007166 | 0.73 | CYP1A2 (0.65) | CYP1A2CYP2A6KDM4EMAPTPABPC1 | |
| SCHEMBL845776 | 0.73 | ALDH1A1 (0.61) | CYP1A2CYP2A6ALDH1A1TSHRCYP2C9 | |
| SCHEMBL5949824 | 0.72 | PARP1 (0.39) | CYP1A2ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL6619213 | 0.71 | CYP1A2 (0.46) | CYP1A2CYP2A6KDM4EMAPTALDH1A1 | |
| SCHEMBL7833173 | 0.71 | CYP1A2 (0.62) | CYP1A2CYP2A6KDM4EMAPTPABPC1 | |
| SCHEMBL5236200 | 0.70 | CYP1A2 (0.48) | CYP1A2CYP2A6KDM4EALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |