SCHEMBL840498

SCHEMBL840498

Cc1cccc(C)c1C(Br)C=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
ALDH1A1 P00352 5/20 0.38
TSHR P16473 2/20 0.38
CYP2A6 P11509 2/20 0.35
CYP1A2 P05177 1/20 0.35
ACHE P22303 1/20 0.33
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TRPA1 O75762 2/20 0.30
CD44 P16070 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19858987 0.86 TRPA1 (0.42) CA1CA2CA7CA9ALDH1A1
SCHEMBL28428912 0.86 CYP1A2 (0.30) CYP2A6CYP1A2
SCHEMBL22833975 0.77 ERN1 (0.32) ALDH1A1
SCHEMBL3410995 0.77 ERN1 (0.32) ALDH1A1
SCHEMBL1573210 0.76 CA1 (0.42) CA1CA2CA7CA9ALDH1A1
SCHEMBL168886 0.76 ESR1 (0.45) CA1CA2CA7CA9ALDH1A1
SCHEMBL6619213 0.75 CYP1A2 (0.46) ALDH1A1TSHRCYP2A6CYP1A2TDP1
SCHEMBL2572781 0.74 CYP2A6 (0.33) ALDH1A1CYP2A6
SCHEMBL14992458 0.74 CYP3A4 (0.38) ALDH1A1ACHETDP1ATM
SCHEMBL14992136 0.74 ALDH1A1 (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115448957-A Novel tetradentate platinum complexes 通用显示公司 2022-12-09 CN disclosed
CN-111732611-B Novel tetradentate platinum complexes 通用显示公司 2022-08-23 CN disclosed
CN-111732611-A Novel tetradentate platinum complexes 通用显示公司 2020-10-02 CN disclosed
CN-106749425-B Novel tetradentate platinum complexes 通用显示公司 2020-07-14 CN disclosed
US-10381580-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-20180151816-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-31 US disclosed
US-20180151816-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-05-31 US disclosed
US-9947880-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-04-17 US disclosed
US-9947880-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-04-17 US disclosed
US-20150028323-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-29 US disclosed
US-20120223634-A1 NOVEL TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2012-09-06 US disclosed
WO-2012116231-A2 NOVEL TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2012-08-30 WO disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10381580-B2 Organic electroluminescent materials and devices TEC, EML4, TPR CA1 2272/4885CA2 1914/4885CA7 3357/4885
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C CA1 3204/4885CA2 621/4885CA7 1840/4885
US-20180151816-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TEC, EML4, TPR CA1 2272/4885CA2 1914/4885CA7 3357/4885
US-20120223634-A1 NOVEL TETRADENTATE PLATINUM COMPLEXES PDCD1LG2, TEC, TPR CA1 1636/4885CA2 1359/4885CA7 2564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.