Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068329 | 0.65 | — | — | |
| SCHEMBL17928655 | 0.60 | — | — | |
| SCHEMBL8009802 | 0.55 | MEN1 (0.31) | MEN1BLMKMT2A | |
| SCHEMBL15186753 | 0.54 | — | — | |
| SCHEMBL13735762 | 0.54 | ALDH1A1 (0.65) | MEN1BLMKMT2A | |
| SCHEMBL7857549 | 0.52 | ALDH1A1 (0.31) | — | |
| SCHEMBL9708912 | 0.51 | ALDH1A1 (0.55) | MEN1BLMKMT2A | |
| SCHEMBL4434457 | 0.51 | MEN1 (0.38) | MEN1BLMKMT2A | |
| SCHEMBL5138845 | 0.50 | KMT2A (0.41) | MEN1BLMKMT2A | |
| SCHEMBL753995 | 0.49 | GDA (0.53) | MEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683781-B1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | METABASIS THERAPEUTICS INC (US) | 2004-04-21 | — | — | EP | disclosed |
| EP-0683781-A4 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE. | GENSIA PHARMA (US) | 1997-05-28 | — | — | EP | disclosed |
| EP-0683781-A1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | GENSIA PHARMACEUTICALS, INC. (US) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994018200-A1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |