Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 5/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660547 | 0.88 | ALDH1A1 (0.39) | KMT2AALDH1A1L3MBTL1MAPK1HIF1A | |
| SCHEMBL661570 | 0.81 | ALDH1A1 (0.51) | KMT2ACNR1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL660255 | 0.79 | ALDH1A1 (0.47) | KMT2AALDH1A1MAPK1HIF1AKDM4E | |
| SCHEMBL27573195 | 0.78 | KMT2A (0.47) | KMT2ACNR1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL287385 | 0.78 | ALDH1A1 (0.46) | KMT2AALDH1A1TDP1L3MBTL1THRB | |
| SCHEMBL18481835 | 0.77 | KMT2A (0.73) | KMT2ACNR1ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7808649 | 0.76 | ALDH1A1 (0.42) | KMT2AALDH1A1TDP1L3MBTL1THRB | |
| SCHEMBL286986 | 0.75 | MAPT (0.46) | KMT2AALDH1A1TDP1L3MBTL1THRB | |
| SCHEMBL659989 | 0.74 | MEN1 (0.44) | KMT2AALDH1A1TDP1L3MBTL1MAPK1 | |
| SCHEMBL661083 | 0.73 | ALDH1A1 (0.39) | KMT2AALDH1A1TDP1L3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | KMT2A 4512/4885CNR1 968/4885ALDH1A1 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.