Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287385 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL7808649 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL661273 | 0.81 | HPGD (0.43) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL660547 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL661083 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL662087 | 0.79 | KMT2A (0.47) | ALDH1A1MAPK1HIF1AMAPTKDM4E | |
| SCHEMBL661570 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPK1HIF1ACA12CA1 | |
| SCHEMBL298933 | 0.76 | RAB9A (0.40) | ALDH1A1MAPK1MAPTKDM4ECA12 | |
| SCHEMBL286985 | 0.73 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1HIF1AERCC5FEN1 | |
| SCHEMBL660293 | 0.71 | HPGD (0.46) | ALDH1A1MAPK1ERCC5FEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | ALDH1A1 676/4885MAPK1 1750/4885HIF1A 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.