Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 4/20 | 0.48 |
| ▸ | CTSV | O60911 | 4/20 | 0.46 |
| ▸ | TACR3 | P29371 | 3/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926223 | 0.81 | CTSS (0.51) | CTSLCTSSCTSBCTSVTACR3 | |
| SCHEMBL6929121 | 0.69 | CTSS (0.52) | CTSLCTSSCTSBCTSVKLKB1 | |
| SCHEMBL16999362 | 0.68 | KDM4E (0.53) | CTSLCTSSCTSVNSD2KLKB1 | |
| SCHEMBL16994018 | 0.68 | KDM4E (0.53) | CTSLCTSSCTSVNSD2KLKB1 | |
| SCHEMBL7462346 | 0.66 | CTSK (0.47) | CTSLCTSSCTSBCTSV | |
| SCHEMBL16999319 | 0.66 | PABPC1 (0.66) | CTSLCTSSCTSVNSD2KMT2A | |
| SCHEMBL16999703 | 0.66 | KDM4E (0.53) | CTSLCTSSCTSVNSD2 | |
| SCHEMBL16993979 | 0.66 | PABPC1 (0.66) | CTSLCTSSCTSVNSD2KMT2A | |
| SCHEMBL16994059 | 0.66 | KDM4E (0.53) | CTSLCTSSCTSVNSD2 | |
| SCHEMBL16999330 | 0.66 | USP30 (0.59) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067894-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2004-09-08 | — | — | EP | claimed |
| EP-1067894-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-01-17 | — | — | EP | claimed |
| WO-1999059526-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-25 | — | — | WO | claimed |