Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.52 |
| ▸ | CTSL | P07711 | 9/20 | 0.52 |
| ▸ | CTSB | P07858 | 8/20 | 0.52 |
| ▸ | CTSV | O60911 | 7/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928352 | 0.92 | CTSL (0.44) | CTSSCTSLCTSBCTSV | |
| SCHEMBL6926223 | 0.89 | CTSS (0.51) | CTSSCTSLCTSBCTSVKLKB1 | |
| SCHEMBL6928739 | 0.83 | CTSL (0.58) | CTSSCTSLCTSBCTSVKMT2A | |
| SCHEMBL6923719 | 0.82 | CTSL (0.55) | CTSSCTSLCTSBCTSVKLKB1 | |
| SCHEMBL7462346 | 0.74 | CTSK (0.47) | CTSSCTSLCTSBCTSV | |
| SCHEMBL6659791 | 0.74 | CTSL (0.47) | CTSSCTSLCTSB | |
| SCHEMBL7464820 | 0.71 | CTSL (0.47) | CTSSCTSLCTSBCTSV | |
| SCHEMBL7462272 | 0.71 | CTSL (0.50) | CTSSCTSLCTSBCTSV | |
| SCHEMBL6927425 | 0.70 | CTSL (0.55) | CTSSCTSLCTSBCTSV | |
| SCHEMBL7473345 | 0.69 | TAS1R3 (0.54) | CTSSCTSLCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | claimed |
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | disclosed |