Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.38 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | GRK5 | P34947 | 2/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6622790 | 0.81 | TNKS (0.39) | TNKSPARP1PARP6PARP15PARP14 | |
| SCHEMBL6626498 | 0.78 | PARP2 (0.39) | TNKSPARP1PARP6PARP15PARP14 | |
| Bromide SCHEMBL4070073 | 0.76 | PARP2 (0.38) | TNKSPARP1PARP6PARP15PARP14 | |
| SCHEMBL841386 | 0.69 | HSP90AB1 (0.39) | JAK2P2RX3P2RX2 | |
| SCHEMBL23330631 | 0.68 | MAPT (0.37) | PARP15PARP10TNKS2PARP2MAPT | |
| SCHEMBL6623696 | 0.66 | APLNR (0.35) | TNKSPARP1PARP6PARP15PARP14 | |
| Bromide SCHEMBL7865974 | 0.63 | ALDH1A1 (0.35) | MAPTALDH1A1 | |
| SCHEMBL2441110 | 0.61 | ALDH1A1 (0.37) | FGFR1MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL4059934 | 0.60 | CHEK1 (0.35) | CHEK1GRK5CSNK1A1LIMK1TYRO3 | |
| SCHEMBL2172710 | 0.60 | NOS3 (0.34) | TNKSPARP1PARP15PARP14PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362335-B1 | — | — | None | — | — | US | disclosed |
| EP-1289994-B1 | PROCESS FOR THE PREPARATION OF 2-AMINO-5,8-DIMETHOXY 1,2,4]TRIAZOLO 1,5-c]PYRIMIDINE | DOW AGROSCIENCES LLC (US) | 2004-03-17 | — | — | EP | disclosed |
| US-6362335-B2 | CONTACTING 3-AMINO-8-METHOXY(1,2,4) TRIAZOLO(4,3-C)PYRIMIDINE COMPOUNDS WITH SODIUM OR POTASSIUM METHOXIDE IN AN ALCOHOL SOLVENT | DOW AGROSCIENCES LLC | 2002-03-26 | — | — | US | disclosed |
| US-20020013230-A1 | Process for the preparation of 2-amino-5, 8-dimethoxy (1,2,4) triazolo (1,5-c) pyrimidine | CORTEVA AGRISCIENCE LLC | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013230-A1 | Process for the preparation of 2-amino-5, 8-dimethoxy (1,2,4) triazolo (1,5-c) pyrimidine | PYM1, THPO, ADH1C | TNKS 165/4885PARP1 493/4885PARP6 1338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.