Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 11/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614581 | 0.86 | CHRM2 (0.69) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7613377 | 0.82 | CHRM1 (0.64) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7615807 | 0.82 | CHRM2 (0.54) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| Iodide SCHEMBL9434717 | 0.81 | CHRM2 (0.53) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7900617 | 0.81 | CHRM1 (0.74) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4029522 | 0.81 | CHRM1 (0.67) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7609678 | 0.80 | CHRM1 (0.69) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7610648 | 0.79 | CHRM2 (0.60) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7616125 | 0.79 | CHRM2 (0.57) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7617382 | 0.79 | CHRM1 (0.71) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355646-A4 | MUSCARINIC RECEPTOR AGONISTS | UNIV TOLEDO (US) | 2004-06-16 | — | — | EP | disclosed |
| EP-1355646-A1 | MUSCARINIC RECEPTOR AGONISTS | UNIVERSITY OF TOLEDO (US) | 2003-10-29 | — | — | EP | disclosed |
| US-6602891-B2 | Muscarinic receptor agonists | THE UNIVERSITY OF TOLEDO | 2003-08-05 | — | — | US | disclosed |
| US-20030032658-A1 | Muscarinic receptor agonists | MESSER WILLIAM S (US) | 2003-02-13 | — | — | US | disclosed |
| WO-2002060444-A1 | MUSCARINIC RECEPTOR AGONISTS | UNIVERSITY OF TOLEDO, THE a University instrumentality of the State of Ohio (US) | 2002-08-08 | — | — | WO | disclosed |
| US-6376675-B2 | PYRIDYL-1,2,5-THIADIAZOLE DERIVATIVES | THE UNIVERSITY OF TOLEDO | 2002-04-23 | — | — | US | disclosed |
| US-20010036953-A1 | Pyridyl-1,2,5-thiadiazole derivatives | TOLEDO, THE UNIVERSITY OF | 2001-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032658-A1 | Muscarinic receptor agonists | CHRM3, CHRM4, CHRM2 | CHRM2 3/4885CHRM4 2/4885CHRM5 5/4885 |
| US-20010036953-A1 | Pyridyl-1,2,5-thiadiazole derivatives | CHRM3, CHRNA3, CHRNA2 | CHRM2 4/4885CHRM4 6/4885CHRM5 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.