Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624568 | 0.79 | NOTUM (0.44) | ALDH1A1HSP90AA1HPGDXBP1ALOX12 | |
| SCHEMBL6626313 | 0.78 | HTR2C (0.46) | HTR2AHTR2CFABP4RHEBP2RX7 | |
| SCHEMBL6626421 | 0.77 | HTR6 (0.39) | ALDH1A1HSP90AA1HPGDXBP1ALOX12 | |
| SCHEMBL6626210 | 0.75 | HTR6 (0.43) | HPGDSLC6A2HTR6 | |
| SCHEMBL6624855 | 0.73 | SLC6A2 (0.50) | HTR2AHTR2CALDH1A1HPGDHTT | |
| SCHEMBL6624704 | 0.69 | HTR6 (0.56) | HTR2AALDH1A1HPGDHTR6 | |
| SCHEMBL24721604 | 0.67 | HTR2A (0.46) | HTR2AHTR2CFABP4RHEBP2RX7 | |
| SCHEMBL2435580 | 0.67 | RHEB (0.66) | HTR2AHTR2CFABP4RHEBP2RX7 | |
| SCHEMBL30373755 | 0.67 | RHEB (0.66) | HTR2AHTR2CFABP4RHEBP2RX7 | |
| SCHEMBL3216695 | 0.67 | HTR2A (0.50) | HTR2AHTR2CFABP4RHEBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |