Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624272 | 0.79 | HTR2A (0.41) | HTR6ALDH1A1HSP90AA1HPGDXBP1 | |
| SCHEMBL6626421 | 0.77 | HTR6 (0.39) | CYP1A2HTR6ALDH1A1HSP90AA1HPGD | |
| SCHEMBL6626210 | 0.75 | HTR6 (0.43) | HTR6HPGDLMNATSHR | |
| SCHEMBL6624855 | 0.73 | SLC6A2 (0.50) | NOTUMHTR6ALDH1A1HPGDHTT | |
| SCHEMBL3141727 | 0.70 | NOTUM (0.46) | NOTUMHSD11B1CYP1A2CYP2A6HTT | |
| SCHEMBL6624704 | 0.69 | HTR6 (0.56) | CYP1A2HTR6ALDH1A1HPGDLMNA | |
| SCHEMBL6624825 | 0.69 | KMO (0.41) | CYP1A2CYP2A6ALDH1A1HPGDPOLB | |
| SCHEMBL7718987 | 0.69 | NOTUM (0.52) | NOTUMHSD11B1CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL1775925 | 0.68 | HTR6 (0.62) | NOTUMCYP1A2HTR6ALDH1A1LMNA | |
| SCHEMBL6624761 | 0.67 | NOTUM (0.40) | NOTUMHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |