Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628543 | 0.89 | SIGMAR1 (0.38) | HTR6ALDH1A1HPGDHTTKDM4E | |
| SCHEMBL6626210 | 0.83 | HTR6 (0.43) | HTR6PTPN1HPGDMAPT | |
| SCHEMBL6624272 | 0.77 | HTR2A (0.41) | HTR6ALDH1A1HSP90AA1HPGDXBP1 | |
| SCHEMBL6624568 | 0.77 | NOTUM (0.44) | HTR6ALDH1A1HSP90AA1HPGDXBP1 | |
| SCHEMBL6625931 | 0.74 | HTR6 (0.38) | HTR6ALDH1A1 | |
| SCHEMBL6624728 | 0.73 | HTR6 (0.43) | HTR6PTPN1HPGDMAPT | |
| SCHEMBL27110791 | 0.73 | HTR6 (0.38) | HTR6PTPN1ALDH1A1TDP1 | |
| SCHEMBL707336 | 0.72 | ALDH1A1 (0.42) | ALDH1A1HSP90AA1HPGDXBP1ALOX12 | |
| SCHEMBL6624855 | 0.72 | SLC6A2 (0.50) | HTR6ALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL1753727 | 0.69 | ALDH1A1 (0.39) | ALDH1A1HSP90AA1HPGDXBP1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |