Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 known ✓ | P30542 | 3/20 | 0.83 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 3/20 | 0.83 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.83 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.83 |
| ▸ | DPP4 | P27487 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.83 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.83 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.83 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.83 |
| ▸ | GAPDH | P04406 | 1/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.83 |
| ▸ | STAT6 | P42226 | 1/20 | 0.83 |
| ▸ | PI4KA | P42356 | 1/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.83 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.83 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.83 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.83 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.83 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL28583342 | 0.98 | ADORA1 (0.83) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL353215 | 0.98 | ADORA1 (0.83) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL353216 | 0.97 | ADORA3 (0.85) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL23093553 | 0.95 | ADORA3 (0.85) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL5600395 | 0.95 | ADORA3 (0.85) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL1746637 | 0.95 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL50788 | 0.95 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL468212 | 0.95 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL3031964 | 0.95 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Vidarabine SCHEMBL7103173 | 0.95 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122075514-A | Use of glycogen phosphatase B agonists for the treatment of neurodegenerative diseases | — | 2026-05-26 | — | — | CN | claimed |
| CN-117551344-B | Low-moisture-absorption nylon material and preparation method thereof | 苏州优利金新材料有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117551344-A | Low-moisture-absorption nylon material and preparation method thereof | 苏州优利金新材料有限公司 | 2024-02-13 | — | — | CN | claimed |
| WO-2023234116-A1 | SKIN TREATMENT DEVICE, OPERATION METHOD FOR OPERATING SKIN TREATMENT DEVICE, SKIN TREATMENT METHOD AND PROGRAM | ヤーマン株式会社 | 2023-12-07 | — | — | WO | claimed |
| CN-114344354-A | Injection for facial fat metabolism | 江苏爱薇诗医疗美容集团股份有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-113101908-A | Hybrid ligand hierarchical pore metal organic framework material and preparation method and application thereof | 华南理工大学 | 2021-07-13 | — | — | CN | claimed |
| CN-108697630-B | Methods and compositions for lightening skin using a chaetomium cupreum cell culture extract | 强生消费者公司 | 2021-05-25 | — | — | CN | claimed |
| CN-112707966-A | Protein and hierarchical pore metal-organic framework compound and preparation method and application thereof | 华南理工大学 | 2021-04-27 | — | — | CN | claimed |
| CN-109928999-B | Boron-containing compound, pharmaceutical composition, and preparation method and application of boron-containing compound | 童永彭 | 2020-11-06 | — | — | CN | claimed |
| US-20200215088-A1 | PALATINOSE FOR ENHANCING DIETARY SUPPLEMENT AND PHARMACEUTICAL DELIVERY | KNELLER BRUCE W (US) | 2020-07-09 | — | — | US | claimed |
| US-20180243205-A1 | METHOD AND COMPOSITION FOR LIGHTENING SKIN USING A CELL CULTURE EXTRACT | KENVUE BRANDS LLC | 2018-08-30 | — | — | US | claimed |
| US-20170340657-A1 | PALATINOSE FOR ENHANCING DIETARY SUPPLEMENT AND PHARMACEUTICAL DELIVERY | KNELLER BRUCE W (US) | 2017-11-30 | — | — | US | claimed |
| US-8409594-B2 | Solid oil-in-water emulsion | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-04-02 | — | — | US | claimed |
| US-8283327-B2 | Palatinose for enhancing dietary supplement and pharmaceutical delivery | KNELLER BRUCE W (US) | 2012-10-09 | — | — | US | claimed |
| EP-2367852-A1 | COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS | Sederma (FR) | 2011-09-28 | — | — | EP | claimed |
| WO-2010067327-A1 | COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS | SEDERMA (FR) | 2010-06-17 | — | — | WO | claimed |
| WO-2010044076-A2 | COSMETIC AND TOPICAL USE OF XANTHOHUMOL INCLUDING BRIGHTENING SKIN COMPLEXION AND REDUCING CUTANEOUS REDNESS | SEDERMA (FR) | 2010-04-22 | — | — | WO | claimed |
| CN-1994272-A | Cosmetic application of mint extract | OREAL (FR) | 2007-07-11 | — | — | CN | claimed |
| US-20060153899-A1 | Palatinose for enhancing dietary supplement and pharmaceutical delivery | KNELLER BRUCE W | 2006-07-13 | — | — | US | claimed |
| US-4067775-A | Process and composition for determining the activity of creatinekinase-MB | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-01-10 | — | — | US | claimed |