Adenosine

Adenosine

SCHEMBL353215

Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.O=P([O-])(O)O.[Na+]

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3

The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 known ✓ P30542 3/20 0.83
ADORA3 known ✓ P0DMS8 3/20 0.83
ADORA2A known ✓ P29274 1/20 0.83
ADORA2B known ✓ P29275 1/20 0.83
SMN1; SMN2 Q16637 3/20 0.83
DPP4 P27487 1/20 0.83
MEN1 O00255 1/20 0.83
SLC28A1 O00337 1/20 0.83
MAP3K7 O43318 1/20 0.83
SLC28A2 O43868 1/20 0.83
GAPDH P04406 1/20 0.83
MAPK1 P28482 1/20 0.83
STAT6 P42226 1/20 0.83
PI4KA P42356 1/20 0.83
KMT2A Q03164 1/20 0.83
PI4K2B Q8TCG2 1/20 0.83
DOT1L Q8TEK3 1/20 0.83
SLC29A1 Q99808 1/20 0.83
PI4K2A Q9BTU6 1/20 0.83
SLC28A3 Q9HAS3 1/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine SCHEMBL662450 0.98 ADORA1 (0.83) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL353216 0.97 ADORA3 (0.85) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL28583342 0.96 ADORA1 (0.83) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL23093553 0.95 ADORA3 (0.85) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL5600395 0.95 ADORA3 (0.85) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL1746637 0.95 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL3046213 0.95 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL468212 0.95 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL3031964 0.95 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Vidarabine SCHEMBL7103173 0.95 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 790 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117467715-A Process for simultaneously preparing D-glutamic acid and L-glutathione by multi-step enzyme method 珠海瑞德林生物有限公司 2024-01-30 CN claimed
CN-116133639-A Formulations and methods for treating inflammatory diseases 维奥梅治疗公司 2023-05-16 CN claimed
US-20230144779-A1 FORMULATIONS AND METHOD FOR TREATMENT OF INFLAMMATORY DISEASES VYOME THERAPEUTICS INC. (US) 2023-05-11 US claimed
CN-109265696-B Preparation method of ceramic water reducing agent 佛山一宇卫士陶瓷材料有限公司 2021-08-20 CN claimed
CN-113101908-A Hybrid ligand hierarchical pore metal organic framework material and preparation method and application thereof 华南理工大学 2021-07-13 CN claimed
WO-2021124301-A1 FORMULATIONS AND METHOD FOR TREATMENT OF INFLAMMATORY DISEASES VYOME THERAPEUTICS INC. (US) 2021-06-24 WO claimed
CN-112707966-A Protein and hierarchical pore metal-organic framework compound and preparation method and application thereof 华南理工大学 2021-04-27 CN claimed
CN-102245643-A Cosmetic composition containing acetylated oligoglucuronans SEDERMA SA 2011-11-16 CN claimed
EP-2367852-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS Sederma (FR) 2011-09-28 EP claimed
WO-2010067327-A1 COSMETIC COMPOSITION CONTAINING ACETYLATED OLIGOGLUCURONANS SEDERMA (FR) 2010-06-17 WO claimed
EP-4149415-B1 SHAMPOO COMPOSITION COMPRISING ALKYL GLUCOSIDE PROCTER & GAMBLE (US) 2026-05-20 EP disclosed
US-12605316-B2 Alkenone-based formulations for topical applications WOODS HOLE OCEANOGRAPHIC INSTITUTION (US) 2026-04-21 US disclosed
EP-4337333-B1 SHAMPOO COMPOSITION PROCTER & GAMBLE (US) 2026-04-15 EP disclosed
WO-2026047750-A1 ODOR REMOVAL FORMULATIONS AND SUBSTRATES COMPRISING THE SAME KRID LABS LLP (IN) 2026-03-05 WO disclosed
US-12533371-B2 Multilayer pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and b vitamins, preparation and uses thereof FERRER INTERNACIONAL, S.A. (ES) 2026-01-27 US disclosed
EP-0852949-A2 Use of alpha-amino-acids for enhancing desmosomal degradation or stratum corneum desquamation SHISEIDO COMPANY LIMITED (JP) 1998-07-15 EP disclosed
EP-0815838-A2 External skin treatment composition SHISEIDO COMPANY, LTD. (JP) 1998-01-07 EP disclosed
EP-0779097-A1 EMULSION COMPOSITION SHISEIDO COMPANY LIMITED (JP) 1997-06-18 EP disclosed
US-4916078-A SUPERIMPOSING FORCE ON FLUID FLOW BOEHRINGER MANNHEIM GMBH (DE) 1990-04-10 US disclosed
US-4898832-A Process for carrying out analytical determinations and means for carrying out this process BOEHRINGER MANNHEIM GMBH (DE) 1990-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605316-B2 Alkenone-based formulations for topical applications CUTA, FLNA, TELO2 ADORA1 742/4885ADORA3 936/4885ADORA2A 1990/4885
US-12533371-B2 Multilayer pharmaceutical or nutraceutical solid dosage forms comprising pyrimidine and/or purine derivatives and b vitamins, preparation and uses thereof P2RY10, TYMP, P2RY12 ADORA1 223/4885ADORA3 191/4885ADORA2A 143/4885
US-20230144779-A1 FORMULATIONS AND METHOD FOR TREATMENT OF INFLAMMATORY DISEASES UACA, TNF, TPMT ADORA1 1287/4885ADORA3 3174/4885ADORA2A 1491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.