Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624793 | 0.76 | SLC6A2 (0.45) | NOTUMSLC6A2HSD11B1 | |
| SCHEMBL6624568 | 0.67 | NOTUM (0.44) | NOTUMHSD11B1 | |
| SCHEMBL1092615 | 0.63 | HSD11B1 (0.57) | NOTUMHSD11B1 | |
| SCHEMBL7718987 | 0.61 | NOTUM (0.52) | NOTUMSLC6A2HSD11B1 | |
| SCHEMBL26099756 | 0.60 | FBP1 (0.36) | — | |
| SCHEMBL516394 | 0.60 | — | — | |
| SCHEMBL13311382 | 0.60 | NOTUM (0.50) | NOTUMSLC6A2 | |
| SCHEMBL13209355 | 0.60 | NOTUM (0.50) | NOTUMSLC6A2HSD11B1 | |
| SCHEMBL25141967 | 0.60 | NOTUM (0.46) | NOTUMSLC6A2HSD11B1 | |
| SCHEMBL12542746 | 0.58 | NOTUM (0.44) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |