Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624985 | 0.84 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6624071 | 0.83 | BRD4 (0.48) | KDM4EALDH1A1HPGDGAABRD4 | |
| SCHEMBL6625269 | 0.80 | HTT (0.46) | KDM4EALDH1A1HPGDGAABRD4 | |
| SCHEMBL8218858 | 0.80 | PARP1 (0.41) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6623859 | 0.80 | PARP1 (0.41) | KDM4EALDH1A1HPGDGAABRD4 | |
| SCHEMBL6628897 | 0.80 | PARP1 (0.41) | KDM4EALDH1A1HPGDGAABRD4 | |
| SCHEMBL6623305 | 0.78 | HSD11B1 (0.45) | KDM4EALDH1A1HPGDGAABRD4 | |
| SCHEMBL6623102 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL6627070 | 0.77 | BRD4 (0.48) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6623944 | 0.75 | PARP1 (0.46) | KDM4EALDH1A1HPGDBRD4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |