Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624847 | 0.84 | KDM4E (0.47) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6624708 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8218858 | 0.75 | PARP1 (0.41) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6624071 | 0.75 | BRD4 (0.48) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL6628897 | 0.73 | PARP1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10BRD4 | |
| SCHEMBL6623859 | 0.73 | PARP1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10BRD4 | |
| SCHEMBL6625269 | 0.73 | HTT (0.46) | ALDH1A1KDM4EMAPTHTTHPGD | |
| SCHEMBL7387395 | 0.71 | ABCB1 (0.49) | ALDH1A1KDM4EDDB1CRBNHTT | |
| SCHEMBL6623305 | 0.71 | HSD11B1 (0.45) | ALDH1A1KDM4EHPGDTSHRBRD4 | |
| SCHEMBL6624149 | 0.67 | PTGDR2 (0.39) | MEN1KMT2ADDB1CRBNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858996-B1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARM CO LTD (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0858996-A1 | NERVE CELL PROTECTIVE AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | disclosed |