Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628897 | 0.83 | PARP1 (0.41) | PARP1BRD4HSD11B1ALDH1A1GAA | |
| SCHEMBL6623859 | 0.83 | PARP1 (0.41) | PARP1BRD4HSD11B1ALDH1A1GAA | |
| SCHEMBL6624071 | 0.83 | BRD4 (0.48) | PARP1BRD4HSD11B1ALDH1A1GAA | |
| SCHEMBL6625269 | 0.83 | HTT (0.46) | PARP1BRD4HSD11B1ALDH1A1GAA | |
| SCHEMBL6623305 | 0.81 | HSD11B1 (0.45) | PARP1BRD4HSD11B1ALDH1A1GAA | |
| SCHEMBL6624847 | 0.80 | KDM4E (0.47) | PARP1BRD4HSD17B1ALDH1A1GAA | |
| SCHEMBL6624211 | 0.75 | PARP1 (0.68) | PARP1 | |
| SCHEMBL6624985 | 0.75 | ALDH1A1 (0.42) | PARP1BRD4ALDH1A1HPGDKDM4E | |
| SCHEMBL6626884 | 0.72 | HTT (0.46) | PARP1BRD4SERPINE1GAAKDM4E | |
| SCHEMBL6623153 | 0.70 | HTT (0.44) | PARP1BRD4HSD17B10ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040331-A | Nerve cell protective agents | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |