Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625451 | 0.90 | FKBP1A (0.46) | FKBP1AHTR2CALDH1A1TSHRCYP3A4 | |
| SCHEMBL6628463 | 0.85 | FKBP1A (0.51) | FKBP1AHTR2CALDH1A1TSHRCYP3A4 | |
| SCHEMBL6625918 | 0.84 | FKBP1A (0.52) | FKBP1AHTR2CALDH1A1TSHRCYP3A4 | |
| SCHEMBL19898539 | 0.84 | HTR2C (0.47) | FKBP1AHTR2CALDH1A1TSHRCYP3A4 | |
| SCHEMBL19898733 | 0.84 | HTR2C (0.47) | FKBP1AHTR2CALDH1A1TSHRCYP3A4 | |
| SCHEMBL19910781 | 0.84 | HTR2C (0.47) | FKBP1AHTR2CALDH1A1TSHRCYP3A4 | |
| SCHEMBL6627266 | 0.84 | PREP (0.48) | FKBP1AHTR2CALDH1A1TSHRCYP3A4 | |
| SCHEMBL9546447 | 0.82 | HTR2C (0.57) | FKBP1AHTR2CALDH1A1CYP3A4NPSR1 | |
| SCHEMBL6628624 | 0.82 | FKBP1A (0.44) | FKBP1AHTR2CALDH1A1TSHRCYP3A4 | |
| SCHEMBL10614922 | 0.80 | HTR2C (0.52) | FKBP1AHTR2CALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098897-B1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMA (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6630472-B1 | Peptidyl-prolyl isomerase inhibitors | PFIZER INC | 2003-10-07 | — | — | US | disclosed |
| CN-1318067-A | Compounds, compsns. and methods for stimulating neuronal growth and elongation | AGOURON PHARMA (US) | 2001-10-17 | — | — | CN | disclosed |
| EP-1098897-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMACEUTICALS, INC. (US) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000004020-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR STIMULATING NEURONAL GROWTH AND ELONGATION | AGOURON PHARMACEUTICALS, INC. (US) | 2000-01-27 | — | — | WO | disclosed |