Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625834 | 0.84 | MGAM (0.34) | LMNAHPGDTSHRHSD17B10 | |
| SCHEMBL6628176 | 0.84 | KMT2A (0.35) | MEN1KMT2AKDM4EHTTTP53 | |
| SCHEMBL9431441 | 0.71 | CYP2C19 (0.44) | MEN1KMT2AKDM4EHTTTP53 | |
| SCHEMBL6625487 | 0.70 | TP53 (0.40) | MEN1KMT2AKDM4EHTTTP53 | |
| SCHEMBL12735602 | 0.68 | PDGFRB (0.50) | MEN1KMT2AKDM4EPDGFRBNPC1 | |
| SCHEMBL11048397 | 0.67 | PDGFRB (0.47) | MEN1KMT2AKDM4EPDGFRBNPC1 | |
| SCHEMBL10886759 | 0.66 | PDGFRB (0.46) | KDM4EPDGFRBNPC1RAB9ACASP3 | |
| SCHEMBL11771726 | 0.65 | KDM4E (0.50) | KDM4EPDGFRBNPC1RAB9ACASP3 | |
| SCHEMBL9255839 | 0.64 | MAPT (0.43) | MEN1KMT2AKDM4EPDGFRBNPC1 | |
| SCHEMBL6598963 | 0.63 | PDGFRB (0.49) | KDM4ETP53PDGFRBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004525942-A | — | — | 2004-08-26 | — | — | JP | claimed |
| US-20040116495-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2004-06-17 | — | — | US | claimed |
| EP-1379241-A1 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2004-01-14 | — | — | EP | claimed |
| WO-2002078699-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-10 | — | — | WO | claimed |
| US-20040116495-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2004-06-17 | — | — | US | disclosed |