Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 9/20 | 0.34 |
| ▸ | GAA | P10253 | 9/20 | 0.34 |
| ▸ | SI | P14410 | 9/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6628176 | 0.87 | KMT2A (0.35) | GAALMNAHPGDTSHR | |
| SCHEMBL6625835 | 0.68 | GAA (0.33) | MGAMGAASIMGAM2HSD17B10 | |
| SCHEMBL6629853 | 0.64 | HTT (0.50) | HPGDTSHR | |
| SCHEMBL24484639 | 0.63 | RAB9A (0.47) | GAALMNAHPGDMETAP2 | |
| SCHEMBL855275 | 0.63 | METAP2 (0.38) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL5924343 | 0.60 | MAPT (0.47) | GAAMETAP2 | |
| SCHEMBL28957521 | 0.60 | METAP2 (0.41) | GAALMNAMETAP2 | |
| SCHEMBL18829052 | 0.60 | METAP2 (0.38) | MGAMGAASIMGAM2LMNA | |
| SCHEMBL2617474 | 0.60 | NPC1 (0.40) | GAALMNAMETAP2 | |
| SCHEMBL6628026 | 0.59 | LMNA (0.52) | MGAMGAASIMGAM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004525942-A | — | — | 2004-08-26 | — | — | JP | claimed |
| US-20040116495-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2004-06-17 | — | — | US | claimed |
| EP-1379241-A1 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2004-01-14 | — | — | EP | claimed |
| WO-2002078699-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-10 | — | — | WO | claimed |
| US-20040116495-A1 | Compounds and methods | SMITHKLINE BEECHAM CORPORATION | 2004-06-17 | — | — | US | disclosed |
| EP-1379241-A1 | COMPOUNDS AND METHODS | SmithKline Beecham Corporation (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002078699-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-10-10 | — | — | WO | disclosed |