Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6785002 | 0.99 | KMT2A (0.41) | KMT2AL3MBTL1FAAHPLA2G10PLA2G5 | |
| SCHEMBL6775961 | 0.96 | KMT2A (0.42) | KMT2AL3MBTL1FAAHPLA2G10PLA2G5 | |
| SCHEMBL6780351 | 0.87 | KMT2A (0.40) | KMT2AL3MBTL1FAAHPLA2G10PLA2G5 | |
| SCHEMBL6778408 | 0.84 | FKBP5 (0.50) | KMT2AL3MBTL1FKBP5POLB | |
| SCHEMBL6625880 | 0.83 | FKBP1A (0.44) | KMT2AL3MBTL1PLA2G10PLA2G5FKBP5 | |
| SCHEMBL6778877 | 0.81 | FKBP5 (0.51) | KMT2AL3MBTL1FKBP5POLB | |
| SCHEMBL6776495 | 0.80 | FKBP5 (0.51) | KMT2AFKBP5FKBP1A | |
| SCHEMBL6776517 | 0.77 | FKBP5 (0.45) | KMT2AL3MBTL1FKBP5SIGMAR1POLB | |
| SCHEMBL2301209 | 0.73 | KMT2A (0.55) | KMT2AL3MBTL1STS | |
| SCHEMBL15436112 | 0.73 | HTR2C (0.46) | SIGMAR1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818643-B1 | 3,9-DIAZABICYCLO(3.3.1)NONAN-2-ONE DERIVATIVES; PEPTIDYL-PROLYL ISOMERASE (PPIASE OR ROTAMASE) INHIBITORS; NEUROPROTECTIVE AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 2004-11-16 | — | — | US | disclosed |