Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624046 | 0.79 | HTR6 (0.57) | HTR6ALDH1A1 | |
| SCHEMBL6626421 | 0.74 | HTR6 (0.39) | HTR6ALDH1A1 | |
| SCHEMBL7737380 | 0.70 | CYP2C19 (0.41) | ALDH1A1TSHRC5AR1 | |
| SCHEMBL452290 | 0.68 | SIGMAR1 (0.47) | ALDH1A1TSHRC5AR1NPC1RAB9A | |
| SCHEMBL6626313 | 0.68 | HTR2C (0.46) | HTR6ALDH1A1 | |
| SCHEMBL6624574 | 0.68 | NOTUM (0.50) | HTR6 | |
| SCHEMBL12744254 | 0.68 | SIGMAR1 (0.47) | ALDH1A1TSHRC5AR1NPC1RAB9A | |
| SCHEMBL4895717 | 0.68 | SIGMAR1 (0.47) | ALDH1A1TSHRC5AR1NPC1RAB9A | |
| SCHEMBL12744248 | 0.68 | SIGMAR1 (0.47) | ALDH1A1TSHRC5AR1NPC1RAB9A | |
| SCHEMBL7147096 | 0.68 | TSHR (0.48) | ALDH1A1TSHRC5AR1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |