Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624793 | 0.81 | SLC6A2 (0.45) | NOTUMCYP1A2CYP2A6HSD11B1HTR6 | |
| SCHEMBL6624568 | 0.78 | NOTUM (0.44) | NOTUMCYP1A2CYP2A6HSD11B1HTR6 | |
| SCHEMBL6624046 | 0.77 | HTR6 (0.57) | CYP1A2HTR6HTR2C | |
| SCHEMBL6626313 | 0.77 | HTR2C (0.46) | HTR6NR3C2SLC6A2SLC6A4HTR2C | |
| SCHEMBL6624761 | 0.76 | NOTUM (0.40) | NOTUMHSD11B1SLC6A2 | |
| SCHEMBL6625582 | 0.76 | NOTUM (0.31) | NOTUM | |
| SCHEMBL6625102 | 0.74 | HTR2C (0.49) | CYP2A6HTR6HTR2C | |
| SCHEMBL6626176 | 0.74 | ALDH1A1 (0.36) | CYP1A2HTR6HTR2C | |
| SCHEMBL1092615 | 0.74 | HSD11B1 (0.57) | NOTUMCYP1A2CYP2A6HSD11B1NR3C2 | |
| SCHEMBL7718987 | 0.71 | NOTUM (0.52) | NOTUMCYP1A2CYP2A6HSD11B1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |