Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625470 | 0.89 | MAPT (0.52) | ALDH1A1MAPTMAPK1PKMHSD17B10 | |
| SCHEMBL6628115 | 0.89 | CNR1 (0.49) | ALDH1A1MAPTMAPK1TSHRMEN1 | |
| SCHEMBL6628598 | 0.88 | MAPT (0.51) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL6625012 | 0.88 | CNR1 (0.46) | ALDH1A1MAPTMAPK1PKMTDP1 | |
| SCHEMBL6668688 | 0.88 | MAPT (0.49) | ALDH1A1MAPTMAPK1ALOX15HSD17B10 | |
| SCHEMBL6626671 | 0.86 | RAD51 (0.47) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL6625246 | 0.84 | HTT (0.49) | ALDH1A1MAPTPKMTDP1TSHR | |
| SCHEMBL6667869 | 0.83 | AR (0.47) | ALDH1A1MAPTMAPK1HSD17B10MEN1 | |
| SCHEMBL6628146 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTMAPK1PKMHSD17B10 | |
| SCHEMBL6623977 | 0.82 | MGAT2 (0.40) | ALDH1A1MAPTMAPK1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373219-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER S.A. (FR) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002081453-A1 | THIOHYDANTOINS AND USE THEREOF FOR TREATING DIABETES | LABORATOIRES FOURNIER SA (FR) | 2002-10-17 | — | — | WO | disclosed |