Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 6/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584506 | 0.82 | CSF1R (0.51) | IMPDH2IDO1TDO2LMNAMEN1 | |
| SCHEMBL9280668 | 0.75 | IMPDH2 (0.51) | IMPDH2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL13516891 | 0.73 | IDO1 (0.52) | IDO1TDO2MEN1KMT2AKDM4E | |
| SCHEMBL31060312 | 0.71 | IMPDH2 (1.00) | IMPDH2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL7812203 | 0.71 | IMPDH2 (0.69) | IMPDH2IDO1TDO2LMNAMEN1 | |
| SCHEMBL17383846 | 0.70 | IMPDH2 (0.73) | IMPDH2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL2013427 | 0.69 | IMPDH2 (0.62) | IMPDH2TDO2LMNAMEN1KMT2A | |
| SCHEMBL26259980 | 0.69 | IDO1 (0.64) | IDO1TDO2CYP2C9CYP3A4 | |
| SCHEMBL7057607 | 0.69 | IMPDH2 (0.53) | IMPDH2IDO1LMNAMEN1KMT2A | |
| SCHEMBL18117823 | 0.69 | GSK3B (0.50) | IDO1TDO2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420015-A1 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2004-05-19 | — | — | EP | disclosed |