Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | LDLR | P01130 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890020 | 0.75 | IMPDH2 (0.43) | IMPDH2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL6772734 | 0.71 | CYP11B2 (0.40) | IMPDH2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL21065289 | 0.71 | HTR6 (0.68) | IMPDH2MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL12318032 | 0.71 | IDO1 (0.50) | KDM4EALDH1A1HPGDHPGDSIDO1 | |
| SCHEMBL7198661 | 0.70 | GSK3B (0.58) | IMPDH2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL31060312 | 0.69 | IMPDH2 (1.00) | IMPDH2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL972964 | 0.69 | HPGDS (0.73) | ALDH1A1CYP1A2HPGDSIDO1LDLR | |
| SCHEMBL6628898 | 0.69 | IMPDH2 (0.55) | IMPDH2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL7812203 | 0.69 | IMPDH2 (0.69) | IMPDH2LMNAMEN1KMT2AKDM4E | |
| SCHEMBL29908698 | 0.69 | IMPDH2 (0.55) | IMPDH2LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002531-A1 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATION SCIENTEFIQUES, S.A.S., A FRANCE CORPORATION | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002531-A1 | Imidazolyl derivatives | TPI1, BCHE, CYP51A1 | IMPDH2 14/4885LMNA 3800/4885MEN1 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.