Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436436 | 0.77 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL28212085 | 0.77 | GNAI3 (0.31) | — | |
| SCHEMBL5560105 | 0.77 | ENPP2 (0.32) | — | |
| SCHEMBL6485343 | 0.75 | DPP8 (0.32) | — | |
| SCHEMBL6475659 | 0.75 | HSD11B1 (0.34) | HSD11B1 | |
| Trifluoroacetic Acid SCHEMBL6628659 | 0.75 | DPP8 (0.38) | HSD11B1LTA4H | |
| SCHEMBL6485499 | 0.74 | CHRM2 (0.37) | — | |
| SCHEMBL6475939 | 0.74 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL3522643 | 0.74 | CKS1B (0.43) | — | |
| SCHEMBL9022637 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949558-A | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2018-04-20 | — | — | CN | disclosed |
| EP-1027332-B1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2004-05-26 | — | — | EP | disclosed |