Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8824402 | 0.82 | GAA (0.50) | TSHRALDH1A1CYP3A4HSD17B10HPGD | |
| SCHEMBL30064915 | 0.79 | TSHR (0.52) | TSHRALDH1A1CYP3A4HSD17B10HPGD | |
| SCHEMBL7752251 | 0.79 | ALDH1A1 (0.48) | TSHRALDH1A1CYP3A4HSD17B10HPGD | |
| SCHEMBL4076360 | 0.79 | TSHR (0.52) | TSHRALDH1A1CYP3A4HSD17B10HPGD | |
| SCHEMBL14742902 | 0.78 | ALDH1A1 (0.59) | TSHRALDH1A1CYP3A4HSD17B10HPGD | |
| SCHEMBL29349435 | 0.75 | JAK2 (0.54) | TSHRALDH1A1CYP3A4HSD17B10HPGD | |
| SCHEMBL65699 | 0.75 | JAK2 (0.54) | TSHRALDH1A1CYP3A4HSD17B10HPGD | |
| SCHEMBL6629658 | 0.75 | TSHR (0.38) | TSHRALDH1A1CYP3A4HSD17B10HPGD | |
| SCHEMBL6185564 | 0.74 | CD44 (0.54) | TSHRALDH1A1CYP3A4HSD17B10HPGD | |
| SCHEMBL5374043 | 0.74 | CDK2 (0.42) | TSHRALDH1A1CYP3A4HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830931-A | DYEING SYNTHETIC HYDROPHOBIC MATERIAL | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | claimed |
| US-6833455-B2 | Coloring plastics | BAYER AKTIENGESELLSCHAFT (DE) | 2004-12-21 | — | — | US | disclosed |
| EP-1314754-B1 | Bridged Perinones/Quinophtalones | BAYER CHEMICALS AG (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-20030139498-A1 | Bridged perinones/quinophthalones | BAYER AKTIENGESELLSCHAFT (DE) | 2003-07-24 | — | — | US | disclosed |
| EP-1118640-B1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2003-07-23 | — | — | EP | disclosed |
| EP-1314754-A1 | Bridged Perinones/Quinophtalones | Bayer Aktiengesellschaft (DE) | 2003-05-28 | — | — | EP | disclosed |
| EP-0827986-B1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2002-03-27 | — | — | EP | disclosed |
| EP-0780444-B1 | Process to manufacture polycyclic compounds | BAYER AG (DE) | 2001-09-05 | — | — | EP | disclosed |
| EP-1118640-A1 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 2001-07-25 | — | — | EP | disclosed |
| US-5955614-A | Bridged perinones/quinophthalones | BAYER AKTIENGESELLSCHAFT (DE) | 1999-09-21 | — | — | US | disclosed |
| US-5830931-A | DYEING SYNTHETIC HYDROPHOBIC MATERIAL | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0827986-A2 | Bridged perinone, quinophthalone and perinone-quinophthalone | BAYER AG (DE) | 1998-03-11 | — | — | EP | disclosed |
| EP-0822804-A1 | HAIR COLORANTS BASED ON PERIMIDINE DERIVATIVES | Clariant GmbH (DE) | 1998-02-11 | — | — | EP | disclosed |
| EP-0780444-A2 | Process to manufacture polycyclic compounds | BAYER AG (DE) | 1997-06-25 | — | — | EP | disclosed |
| US-5621027-A | Dyestuffs for bulk dyeing plastics | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| WO-1996033692-A1 | HAIR COLORANTS BASED ON PERIMIDINE DERIVATIVES | CLARIANT GMBH (DE) | 1996-10-31 | — | — | WO | disclosed |
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0683212-A1 | New dyes for the bulk dyeing of synthetic materials | BAYER AG (DE) | 1995-11-22 | — | — | EP | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |
| US-4024144-A | SULFONIC ACID GROUPS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139498-A1 | Bridged perinones/quinophthalones | CYP11B1, CYP1B1, CYP11B2 | TSHR 3697/4885ALDH1A1 310/4885CYP3A4 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.