Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.44 |
| ▸ | DRD5 | P21918 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6629424 | 0.77 | HTR7 (0.43) | KMT2AHTR2CHTR2B | |
| SCHEMBL6629235 | 0.77 | MAPT (0.55) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL1444364 | 0.71 | QPCT (0.55) | — | |
| SCHEMBL1443392 | 0.69 | QPCT (0.53) | — | |
| SCHEMBL6415386 | 0.68 | HTR2C (0.61) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL1445362 | 0.64 | QPCT (0.55) | — | |
| SCHEMBL14675329 | 0.64 | TUBB4A (0.50) | ALDH1A1MAPTTSHR | |
| SCHEMBL6410260 | 0.63 | HTR2C (0.57) | MEN1KMT2AMAPTL3MBTL1LMNA | |
| SCHEMBL4185628 | 0.63 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL30873099 | 0.63 | KDM4E (0.44) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465630-A1 | CYCLIC UREA DERIVATIVES WITH 5-HT2C RECEPTOR ACTIVITY | GLAXO GROUP LIMITED (GB) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057220-A1 | CYCLIC UREA DERIVATIVES WITH 5-HT2C RECEPTOR ACTIVITY | GLAXO GROUP LIMITED (GB) | 2003-07-17 | — | — | WO | disclosed |