Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 6/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.67 |
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | PKLR | P30613 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | USP8 | P40818 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359105 | 0.96 | BCL2 (0.72) | BCL2MCL1PTPRCPKLRMEN1 | |
| SCHEMBL23968936 | 0.88 | BCL2 (0.54) | BCL2MCL1PKLRCYP1A2MAOA | |
| SCHEMBL7979992 | 0.86 | BCL2 (0.91) | BCL2MCL1PTPRCPKLRCYP1A2 | |
| SCHEMBL24730390 | 0.86 | PTPRC (0.59) | BCL2MCL1PTPRCCYP1A2USP8 | |
| SCHEMBL2769983 | 0.81 | BCL2 (1.00) | BCL2MCL1PTPRCPKLRMEN1 | |
| SCHEMBL571761 | 0.81 | MEN1 (0.63) | BCL2MCL1PTPRCCYP1A2USP8 | |
| SCHEMBL11072946 | 0.77 | BCL2 (0.67) | BCL2MCL1PTPRCPKLRCYP1A2 | |
| SCHEMBL3698733 | 0.77 | MCL1 (0.67) | BCL2MCL1PTPRCPKLRCYP1A2 | |
| SCHEMBL22233097 | 0.77 | PTPRC (0.50) | BCL2MCL1PTPRCCYP1A2USP8 | |
| SCHEMBL17637911 | 0.77 | ELANE (0.52) | BCL2MCL1PTPRCCYP1A2USP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9978950-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2018-05-22 | — | — | US | disclosed |
| US-9837617-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-9837617-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-20170301865-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-10-19 | — | — | US | disclosed |
| US-20170301865-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-10-19 | — | — | US | disclosed |
| US-20160190466-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-30 | — | — | US | disclosed |
| US-20160190466-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-06-30 | — | — | US | disclosed |
| WO-2015022051-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-02-19 | — | — | WO | disclosed |
| EP-0987260-B1 | Photochromic spirofluorenopyrans | RODENSTOCK GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6331625-B1 | EYEGLASS LENSES; RAPID COLOR AND BRIGHTNESS ADJUSTMENT | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-12-18 | — | — | US | disclosed |
| US-6225466-B1 | FOR ARTICLES MADE OF SYNTHETIC RESIN MATERIALS; RAPID DARKENING AND BRIGHTENING RATES, DURABILITY | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-05-01 | — | — | US | disclosed |
| EP-0987260-A1 | Photochromic spirofluorenopyrans | Optische Werke G. Rodenstock (DE) | 2000-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160190466-A1 | MATERIALS FOR ELECTRONIC DEVICES | SDHB, SDHA, ETFB | BCL2 4263/4885MCL1 3723/4885PTPRC 4200/4885 |
| US-20170301865-A1 | MATERIALS FOR ELECTRONIC DEVICES | SDHB, SDHA, ETFB | BCL2 4263/4885MCL1 3723/4885PTPRC 4200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.