Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5646582 | 0.85 | MLYCD (0.58) | MLYCDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL17865780 | 0.84 | MLYCD (0.77) | MLYCDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL12421889 | 0.80 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL19938019 | 0.80 | MLYCD (0.67) | MLYCDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL12243059 | 0.78 | MLYCD (0.69) | MLYCDNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5687748 | 0.78 | MLYCD (0.69) | MLYCDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL7214977 | 0.78 | MLYCD (0.60) | MLYCDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL7214982 | 0.78 | MLYCD (0.60) | MLYCDNPC1RAB9ASMN1; SMN2NAMPT | |
| SCHEMBL28813505 | 0.77 | ALDH1A1 (0.68) | SMN1; SMN2KMT2AALDH1A1POLBNFKB1 | |
| SCHEMBL5648352 | 0.77 | RAB9A (0.61) | MLYCDNPC1RAB9ASMN1; SMN2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458374-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051841-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |