SCHEMBL6630440

SCHEMBL6630440

O=S(=O)(O)c1cc2[c]c(O)ccc2cc1S(=O)(=O)O

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.35
ALDH1A1 P00352 2/20 0.35
CASP6 P55212 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
NT5E P21589 1/20 0.33
MPL P40238 3/20 0.33
CTRC Q99895 1/20 0.32
NSD2 O96028 2/20 0.31
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
HIF1A Q16665 1/20 0.30
DUSP3 P51452 1/20 0.30
PTPN5 P54829 1/20 0.30
PTPN11 Q06124 1/20 0.30
PGAM1 P18669 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6631385 0.78 ALDH1A1 (0.47) HSD17B10ALDH1A1CASP6CYP2C9CYP2C19
SCHEMBL6632057 0.76 ALDH1A1 (0.49) HSD17B10ALDH1A1CASP6CYP2C9CYP2C19
SCHEMBL6630604 0.74 ALDH1A1 (0.42) HSD17B10ALDH1A1CASP6CYP2C9CYP2C19
SCHEMBL6635201 0.73 TTR (0.44) HSD17B10ALDH1A1MPLNSD2HIF1A
SCHEMBL6631669 0.70 CASP6 (0.33) HSD17B10ALDH1A1CASP6CYP2C9CYP2C19
SCHEMBL7066887 0.70 NT5E (0.44) HSD17B10ALDH1A1CASP6CYP2C9CYP2C19
SCHEMBL6632276 0.70 COMT (0.38) HSD17B10ALDH1A1MPLLMNAHPGD
SCHEMBL6632348 0.69 TTR (0.37) HSD17B10ALDH1A1CYP2C9CYP2C19MPL
SCHEMBL6631715 0.69 CTRB1 (0.38) HSD17B10ALDH1A1CYP2C9CYP2C19MPL
SCHEMBL9618721 0.69 CTRB1 (0.38) HSD17B10ALDH1A1CYP2C9CYP2C19MPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
EP-1441013-A1 WATERCOLOR INK Mitsui Chemicals, Inc. (JP) 2004-07-28 EP disclosed