SCHEMBL6632276

SCHEMBL6632276

O=S(=O)(O)c1ccc(O)[c]c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
COMT P21964 1/20 0.38
AURKA O14965 1/20 0.38
AURKB Q96GD4 1/20 0.38
TSHR P16473 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TTR P02766 1/20 0.35
LMNA P02545 2/20 0.34
PGAM1 P18669 1/20 0.34
CYP1A2 P05177 2/20 0.34
MYC P01106 1/20 0.33
CTRB1 P17538 1/20 0.33
TNNI3 P19429 1/20 0.33
TNNT2 P45379 1/20 0.33
TNNC1 P63316 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
MPL P40238 2/20 0.33
HIF1A Q16665 2/20 0.33
HSD17B10 Q99714 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6632205 0.75 COMT (0.38) COMTAURKAAURKBTTRLMNA
SCHEMBL6635201 0.72 TTR (0.44) COMTAURKAAURKBTTRCYP1A2
SCHEMBL6632348 0.72 TTR (0.37) AURKAAURKBTSHRTTRCYP1A2
SCHEMBL176809 0.71 TTR (0.38) COMTAURKAAURKBTSHRSMN1; SMN2
SCHEMBL6630440 0.70 HSD17B10 (0.35) LMNAPGAM1MPLHIF1AHSD17B10
SCHEMBL5683924 0.69 PGAM1 (0.45) COMTAURKAAURKBTSHRSMN1; SMN2
SCHEMBL9618721 0.69 CTRB1 (0.38) TSHRSMN1; SMN2TTRPGAM1CYP1A2
SCHEMBL6631715 0.69 CTRB1 (0.38) TSHRSMN1; SMN2TTRPGAM1CYP1A2
SCHEMBL6632545 0.69 TTR (0.49) COMTAURKAAURKBTTRCYP1A2
SCHEMBL28182070 0.68 GABRA1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040231558-A1 Has a clear hue, high light fastness and high moisture resistance MITSUI CHEMICALS, INC. (JP) 2004-11-25 US disclosed
EP-1441013-A1 WATERCOLOR INK Mitsui Chemicals, Inc. (JP) 2004-07-28 EP disclosed