Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CDC25B | P30305 | 3/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6633846 | 0.98 | ALDH1A1 (0.37) | ALDH1A1MAOAMAOBPDGFRAFER | |
| SCHEMBL168935 | 0.71 | PDGFRA (0.52) | ALDH1A1MAOAMAOBPDGFRAFER | |
| SCHEMBL224635 | 0.71 | ALOX5 (0.41) | HTTGAALMNASMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL7159864 | 0.70 | ALOX5 (0.39) | HTTGAALMNASMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL6760431 | 0.70 | ALOX5 (0.39) | HTTGAALMNASMN1; SMN2NPSR1 | |
| SCHEMBL7323881 | 0.69 | KDM4E (0.50) | ALDH1A1TDP1ALOX15GSK3BMEN1 | |
| SCHEMBL18209132 | 0.68 | ALOX5 (0.34) | — | |
| SCHEMBL1096641 | 0.65 | MAOA (0.36) | ALDH1A1MAOAMAOBPDGFRAFER | |
| SCHEMBL3590696 | 0.65 | CDC25B (0.44) | ALDH1A1MAOAMAOBPDGFRAFER | |
| Biphenyl SCHEMBL12979723 | 0.65 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399450-A1 | BENZOXAZEPINE DERIVATIVES AND THEIR USE AS AMPA RECEPTOR STIMULATORS | Akzo Nobel N.V. (NL) | 2004-03-24 | — | — | EP | disclosed |
| WO-2002100865-A1 | BENZOXAZEPINE DERIVATIVES AND THEIR USE AS AMPA RECEPTOR STIMULATORS | AKZO NOBEL N.V. (NL) | 2002-12-19 | — | — | WO | disclosed |